Common Bone Marrow Disease

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Bone Marrow Transplant (BMT) Treatments:

  1. Autologous Bone Marrow Transplant
    • Using the patient’s own stem cells.
  2. Allogeneic Bone Marrow Transplant
    • Using donor stem cells from a matched sibling, unrelated donor, or haploidentical donor.
  3. Haploidentical Bone Marrow Transplant
    • Transplant from a half-matched donor, usually a family member.
  4. Matched Sibling Donor (MSD) Transplant
    • Transplant using stem cells from a genetically matched sibling.
  5. Matched Unrelated Donor (MUD) Transplant
    • Using stem cells from an unrelated donor with a close genetic match.
  6. Umbilical Cord Blood Transplant
    • Using stem cells from umbilical cord blood.
  7. Stem Cell Transplant for Autoimmune Diseases
    • Particularly for diseases like Multiple Sclerosis, Scleroderma, etc.
  8. Reduced Intensity Conditioning (RIC) BMT
    • A less aggressive preparatory regimen for elderly or frail patients.
  9. CAR-T Cell Therapy
    • A type of immunotherapy where T-cells are modified to attack cancer cells.

Hematology Treatments:

  1. Induction Chemotherapy
    • Intensive chemotherapy used as an initial treatment to reduce cancer burden.
  2. Targeted Therapy
    • Treatment using drugs that target specific molecules involved in cancer growth (e.g., Tyrosine Kinase Inhibitors).
  3. Immunotherapy
    • Boosting the immune system’s ability to fight cancer (e.g., Monoclonal Antibodies).
  4. High-Dose Chemotherapy
    • Used to kill cancer cells before a bone marrow transplant.
  5. Maintenance Chemotherapy
    • Lower-dose chemotherapy to prevent cancer from returning post-transplant.
  6. Transfusions (Red Blood Cells, Platelets)
    • Supportive care for anemia or low blood count due to hematologic disorders.
  7. Leukapheresis
    • Removal of excess white blood cells in cases of leukemia.
  8. Photopheresis
    • A treatment where blood is treated with ultraviolet light to help immune system response, especially in graft-versus-host disease (GVHD).
  9. Antibody-Based Therapies (Rituximab, Blinatumomab)
    • Used for targeting specific cancer cells in blood cancers like lymphoma or leukemia.
  10. Plasmapheresis
  • Removing and replacing plasma from the blood to treat conditions like multiple myeloma or certain autoimmune diseases.
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